47 Comments

  1. Good videos in general on this channel but this one has a nonsense conclusion. Author here jumps to conclusion by swithing brain off. He states correctly, that if one has low T level, increasing to average level would help. Then he also states correctly, that increasing T above natural range will help. So, we see clear increase in MM building potential by increasing T level on two sides of spectrum. Then, he states that increasing in the middle (from average to the high level but not above natural) does not work the same way. Yes there is lack of evidence, but lack of evidence does not imply that it does not happen. Lack of evidence means that it is simply not researched yet. So you can't just jump into conclusion that it does not happen if there is no evidence it does. It would be very unusual if something works on both sides of spectrum but does not work in the middle. I can't recall of any such mechanism out there (although, might exist). And finally, when you draw such wierd conclusion that something works on both sides of spectrum but does not in the middle, you must give at least one plausible explanation why that would happen. If you don't have one, then you should conclude that lack of evidence does not disprove effect, but proves lack of reasearch in the area, and effect is most probably still there as every logic dictates it is. Now with all this being said we know that changing T level naturally is not easy task and as such will have minimal to no real world benefit for an average lifter.

  2. I have a BS in Biology so I'm generally familiar with a lot of the concepts and jargon in evidence based channels like yours. However, I was pre-med so I focused more on life science, microbiology, and more clinical topics. As such, I'm not as familiar with the specifics of physiology, endocrinology, and cell biology as it relates to exercise science and metabolics. Your videos are very helpful for filling in some of the pieces I'm missing but I'd like to be able to do more research on my own. So I really appreciate the article citations shown directly in the video since it gives me a good place to start. Thank you

  3. Hey James, is there any evidence that men who naturally/genetically have higher testosterone, as in, are sitting in the upper percentiles, are able to put on muscle more easily? I distinguish this from someone who is in the moderate range and then increases it acutely into the high range?

  4. I think it's funny when gym bros try to micro-manage their T levels, "to maximize gainzzz". If they put that much work into their actual workout, they'd be seeing those gains.

  5. If you go from 300 to 600 then that's doubling your level so you would expect that to have an significant effect. If you increase from 600 too 900 that's a 50% increase and though it's a reasonable increase its half of the increase in relative terms for the ones which started at 300.

  6. Can you do a video about DIM (Diindolylmethane). I am see TONS of Youtubers trying to explain how DIM can reduce gynocomastia and increase muscle growth. Have you heard of this and if so does it really help?

  7. But wouldn't it be fair to say that because the research isn't clear if there isn't a benefit to increasing your test and there isn't any real risks to increasing it you should try and increase it anyway

  8. I’m getting a common theme in your videos: do the work. Interesting take. I’m wondering how that plays out in real life…🧐 What’s your angle and where can I pay for this obvious hack?

  9. Something else to consider: I officially have hypogonadism. My number is/was 175. My testicles had quit working. I was this way (and this is a guestimation for about 8 years, probably slowly just got worse). Through that time it is mostly the mental issues that caused problems. The inability to focus, brain fog, depression, out burst of anger… you name it I had it. Along with that I did have an overall feeling a muscle achyness and was lethargic. Now that I've been on TRT replacement for a few years (average about 600 now). I have put on more muscle not a screaming amount but I am doing better. But here is where the research needs to figure out. Mentally now, I am great! I have a much better outlook on life, my moods are even keel. I want to eat better, I want to exercise and I find joy in those things and many other things in life like I once did before the crash. Is the effects of testosterone only physical/muscle. Or does it have more to do with brain and organ fuctions that will make a man more like himself and so naturally, the muscle mass goes up? Or is it a combination of both mental and physical forms of help?

  10. the claim of Schoenfeld is ridiculous and pathetic for an academic researcher…there is absolutely no evidence to support his claim…while there is enough evidence to support the claim that testosterone levels are not really correlated negatively with age (as you mention and many people still believe…), but rather positively with physical activity levels even when controlling for age…and the same holds for muscle mass…

  11. I'm willing the wager that the same people who are clamoring for "test boosters", are also the same people who have a trash programs and a garbage diets. I have an endocrine disorder which leaves me on the low side of normal testosterone. There's literally no difference in performance, or my ability to gain muscle. Actually, because I'm older and have never stopped learning, it's easier for me to bulk up now than when I was younger.

  12. Hello James, What were the common percentages of increase of T levels within the group who started from already normal T levels in Bhasin-2001? Could it be that the reason for the lack of significant increase of muscle mass in this group is the fact, that if someone already has a normal T level, then usually he can increase it naturally only by a small percentage? for example going from 600 to 700 is only about 17% increase, which surely will have no or negligible effect, but if someone goes from 500 to 950 (not sure if it's possible naturally though), that's 90% increase, almost double: my bet is that such increase can have significant effect. what would be your guess about it? Cheers!

  13. I absolutely love your channel. Through your content, I've been able to filter out so much of anecdotal BS within the Fitness Industry and motivated me to review studies and researching much closer.

    Keep up the fantastic work! The work you do (not to mention the handful of others with a similar take on using media to educate) is changing the rails on the bullet train that is this industry.

    P.S. never lose the accent! Study show accents increase efficacy of educating by 96.67%

  14. When testing for low test levels, is it possible to be in the normal range but have low levels of 'free' testosterone. And can increased levels of free testosterone whilst still being within the total average be beneficial?

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